Spurs, who have qualified for the competition for the first time in their history, will face Rafa Benitez's side, Werder Bremen and FC Twente in Group A.
Harry Redknapp's men qualified after finishing fourth in the Premier League last season and they overcame Swiss side Young Boys 6-3 on aggregate in the qualifiying round.
Group A
Inter Milan, Werder Bremen, Tottenham, FC Twente
Group B
Lyon, Benfica, Schalke, Hapoel Tel-Aviv
Group C
Manchester United, Valencia, Rangers, Bursaspor
Group D
Barcelona, Panathinaikos, FC Copenhagen, Rubin Kazan
Group E
Bayern Munich, AS Roma, Basel, CFR Cluj
Group F
Chelsea, Marseille, Spartak Moscow, Zilina
Group G
AC Milan, Real Madrid, Ajax, Auxerre
Group H
Arsenal, Shakhtar Donetsk, Braga, Partizan Belgrade
Source: PA
Source: PA