Van der Vaart missed training on Tuesday and went for a scan on an ankle knock, while Bale picked up a shoulder injury in Saturday's north London derby win at Arsenal.
Robbie Keane trained following an ankle problem but Sandro is ineligible and there are still concerns over Niko Kranjcar (calf) and Giovani dos Santos (groin), while captain Ledley King (groin), Michael Dawson (ligament damage), Jamie O'Hara (back) and Jonathan Woodgate (groin) are long-term absentees.
Source: PA
Source: PA