Keane returns to Brian Kerr's squad after sitting out the Republic's last two qualifiers through injury.
Steven Carr and Gary Doherty are also included in the 22-man squad for the game with the Swiss in Basel on October 11th.
ROI: Given (Newcastle), Breen (Sunderland), Carr (Tottenham), Carsley (Everton), Colgan (Stockport), Connolly (West Ham), Doherty (Tottenham), Duff (Chelsea), Finnan (Liverpool), Harte (Leeds), Healey (Sunderland), Holland (Charlton), Kavanagh (Cardiff), Keane (Tottenham), Kilbane (Everton), Kinsella (Aston Villa), McPhail (Nottingham Forest), Morrison (Birmingham City), Murphy (West Bromwich Albion), O’Brien (Newcastle), O’Shea (Manchester United), Reid (Blackburn).